黑色素瘤是一种常见恶性肿瘤,其临床表现可辅助医生进行诊断和制定治疗方案。黑色素瘤的早期诊断对于提高治愈率和预后非常重要。黑色素瘤最常见于那些有明显皮肤病变的部位,尤其是在常常暴露于阳光下的区域。常见临床表现包括黑色素瘤的颜色、大小、形态、边界以及病变的变化趋势。首先,黑色素瘤的颜色是诊断的重要指标之一。黑色素瘤通常呈深褐色或黑色,但也有少数患者的黑色素瘤呈灰色、蓝色甚至红色。任何新出现的病变应该引起注意,尤其是颜色较深、不均匀或颜色发生明显变化的病变。其次,黑色素瘤的大小也是临床表现的重要方面。通常来说,直径超过6毫米的黑色素瘤更有可能是恶性的,但也有些早期黑色素瘤可能小于6毫米。因此,如果存在其他可疑表现,即使病变很小,也应该进行进一步的检查和评估。第三,黑色素瘤的形态和边界也是诊断的重要指标。良性黑色素瘤通常呈现出良好定义的边界,形态规整;而恶性黑色素瘤的边界通常不规则,并且形态各异。不规则的形态和边界可能提示黑色素瘤已经向周围组织扩散。最后,黑色素瘤的变化趋势也对诊断至关重要。任何黑色素瘤在短期内变得更大、形态变化明显或颜色不均匀时,都应引起医生的重视。这些变化可能意味着黑色素瘤已经有恶变或发展成为其他类型的肿瘤。总之,黑色素瘤的临床表现提供了重要的诊断线索,帮助医生评估病变的恶性程度和进一步的治疗方案。任何新出现的、颜色深、大小大、形态边界不规则或有变化的黑色素瘤都应该引起医生的警惕,进行进一步的检查。早期诊断和治疗是预防黑色素瘤扩散和提高生存率的关键。因此,对黑色素瘤的临床表现需要高度关注和准确评估。【参考译文】The clinical manifestations of malignant melanoma are of great importance in the diagnosis and treatment of this condition. Malignant melanoma is a common malignant tumor of the skin, and its clinical manifestations can assist doctors in making a diagnosis and developing treatment plans. Early diagnosis of melanoma is crucial for improving the cure rate and prognosis.Malignant melanoma is most commonly found in areas of the skin with obvious lesions, especially in areas that are frequently exposed to sunlight. Common clinical manifestations include the color, size, shape, borders, and changes in the lesions of the melanoma.Firstly, the color of the melanoma is an important indicator for diagnosis. Melanoma usually appears as dark brown or black, but in some cases, it may be gray, blue, or even red. Any newly appearing lesion should be carefully observed, especially if it is dark, uneven in color, or showing obvious color changes.Secondly, the size of the melanoma is also an important aspect of clinical manifestation. Generally, melanomas with a diameter greater than 6 millimeters are more likely to be malignant, but there are some early-stage melanomas that may be smaller than 6 millimeters. Therefore, if there are other suspicious signs, further examination and evaluation should be conducted, even if the lesion is small.Thirdly, the shape and borders of the melanoma are also important indicators for diagnosis. Benign melanoma usually has well-defined borders and regular shapes, whereas malignant melanoma often has irregular borders and diverse shapes. Irregular shapes and borders may indicate that the melanoma has spread to the surrounding tissues.Lastly, changes in the melanoma are crucial for diagnosis. Any melanoma that becomes larger, significantly changes in shape, or shows uneven coloration within a short period of time should be carefully evaluated. These changes may indicate that the melanoma has become malignant or has transformed into another type of tumor.In conclusion, the clinical manifestations of malignant melanoma provide important diagnostic clues to help doctors assess the degree of malignancy and develop further treatment plans. Any newly appearing melanoma, as well as those that are dark in color, large in size, irregularly shaped, or show changes, should be given careful attention by doctors and further examination. Early diagnosis and treatment are key to preventing the spread of malignant melanoma and improving survival rates. Therefore, the clinical manifestations of malignant melanoma need to be closely monitored and accurately assessed.